Open AccessExamination of Streptococcus mutans for immunoglobulin G Fc reactivity
Author(s) -
C Shea,
Joseph J. Ferretti
Publication year - 1981
Publication title -
infection and immunity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.508
H-Index - 220
eISSN - 1070-6313
pISSN - 0019-9567
DOI - 10.1128/iai.34.3.851-855.1981
Subject(s) - microbiology and biotechnology , agglutination (biology) , antibody , biology , serotype , immunoglobulin g , streptococcus mutans , streptococcus mitis , streptococcus , staphylococcus aureus , enterococcus faecalis , streptococcaceae , immunoglobulin a , streptococcus salivarius , streptococcus pneumoniae , bacteria , immunology , antibiotics , genetics
Representative strains of oral streptococci were tested for Fc immunoglobulin G (IgG) reactivity by two different techniques, agglutination of rabbit-IgG sensitized sheep erythrocytes and uptake of human and rabbit 125I-radiolabeled IgG. None of the S. mutans serotypes a through e reacted with the Fc region of either human or rabbit IgG. Additionally, other streptococci such as S. sanguis, S. salivarius, S. faecalis, and S. mitis failed to show appreciable Fc reactivity as assayed by these techniques. The group A, C, and G streptococci, previously shown to possess Fc reactivity, proved to be reactive in these experiments, as did a protein A-containing strain of Staphylococcus aureus.
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