Open AccessDual Transcriptomics To Determine Gamma Interferon-Independent Host Response to Intestinal Cryptosporidium parvum Infection
Author(s) -
Gina M Gallego-López,
Carolina Mendoza Cavazos,
Andrés M. Tibabuzo Perdomo,
Andrew Garfoot,
Roberta M. O’Connor,
Laura J. Knoll
Publication year - 2022
Publication title -
infection and immunity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.508
H-Index - 220
eISSN - 1070-6313
pISSN - 0019-9567
DOI - 10.1128/iai.00638-21
Subject(s) - cryptosporidium parvum , biology , microbiology and biotechnology , toxoplasma gondii , parasite hosting , immune system , apicomplexa , interferon , interferon gamma , transcriptome , virology , gene , gene expression , immunology , antibody , plasmodium falciparum , genetics , malaria , world wide web , computer science
Animals with a chronic infection of the parasiteToxoplasma gondii are protected against lethal secondary infection with other pathogens. Our group previously determined that solubleT. gondii antigens (STAg) can mimic this protection and be used as a treatment against several lethal pathogens.