Open Accessβ-Propiolactone Vapor Decontamination
Author(s) -
Robert K. Hoffman,
Lee M. Buchanan,
David R. Spiner
Publication year - 1966
Publication title -
applied microbiology
Language(s) - English
Resource type - Journals
ISSN - 0003-6919
DOI - 10.1128/am.14.6.989-992.1966
Subject(s) - human decontamination , environmental science , vapor phase , aqueous solution , process engineering , nuclear engineering , waste management , chemical engineering , materials science , chemistry , computer science , engineering , thermodynamics , physics , organic chemistry
Although β-propiolactone (BPL) is an effective vapor-phase decontaminant for enclosed areas, some problems have been encountered in its use. Adequate air circulation during BPL dissemination could eliminate most of these problems. It is recommended that, when decontaminating the ordinary building or laboratory, the amount of BPL sprayed be changed from the previously suggested 1 gal/16,000 cubic ft of space to 1 gal/25,000 cubic ft. The use of aqueous BPL solutions and thermal-type generators is not recommended.
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