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β-Propiolactone vapor treatment of vaccine production facilities has been shown to be approximately 90% effective in the elimination of large quantities of Simian virus-40 (SV40 ). The use of a rapid fluorescent-antibody assay for the detection of SV40 was also studied.

β-Propiolactone Decontamination of Simian Virus-40 as Determined by a Rapid Fluorescent-Antibody Assay