Open AccessA modulator of wild-type glucocerebrosidase improves pathogenic phenotypes in dopaminergic neuronal models of Parkinson’s disease
Author(s) -
Lena F. Burbulla,
Sohee Jeon,
Jianbin Zheng,
Pingping Song,
Richard B. Silverman,
Dimitri Krainc
Publication year - 2019
Publication title -
science translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.819
H-Index - 216
eISSN - 1946-6242
pISSN - 1946-6234
DOI - 10.1126/scitranslmed.aau6870
Subject(s) - glucocerebrosidase , phenotype , dopaminergic , parkinson's disease , neuroscience , disease , biology , clinical phenotype , substantia nigra , medicine , dopamine , genetics , pathology , gene
New small-molecule modulators of wild-type glucocerebrosidase improve pathogenic phenotypes in different cellular models of Parkinson’s disease.
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