Open AccessCryo–electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex
Author(s) -
Julien Bous,
Hélène Orcel,
Nicolas Floquet,
C. Leyrat,
Joséphine Lai-Kee-Him,
Gérald Gaibelet,
Aurélie Ancelin,
Julie SaintPaul,
Stefano Trapani,
Maxime Louet,
Rémy Sounier,
Hélène Déméné,
Sébastien Granier,
Patrick Bron,
Bernard Mouillac
Publication year - 2021
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abg5628
Subject(s) - vasopressin , g protein coupled receptor , arginine vasopressin receptor 2 , vasopressin receptor , receptor , arginine , microbiology and biotechnology , chemistry , biophysics , antidiuretic , signal transduction , endocrinology , biology , medicine , biochemistry , amino acid
Structures of the AVP-V2R-Gs protein complex provide molecular insights into the function of this clinically relevant target.