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Banking feces: a new frontier for public blood banks?
Author(s) -
Jørgensen Simon Mark Dahl,
Hvas Christian Lodberg,
Dahlerup Jens Frederik,
Mikkelsen Susan,
Ehlers Lars,
Hammeken Lianna Hede,
Licht Tine Rask,
Bahl Martin Iain,
Erikstrup Christian
Publication year - 2019
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/trf.15422
Subject(s) - fecal bacteriotherapy , business , feces , clostridioides , legislation , medicine , environmental health , intensive care medicine , biology , clostridium difficile , antibiotics , ecology , political science , microbiology and biotechnology , law
Fecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridioides difficile infection and is potentially beneficial in other microbiota‐related disorders. The provision of FMT in routine clinical practice requires an extensive infrastructure that is reliant on voluntary donors. Alongside an increasing demand for FMT, the logistic barriers of a large‐scale donor‐dependent operation and the difficulties among health authorities to regulate FMT limit the dissemination of sustainable FMT services. Blood centers are large organizations that handle a multitude of donor‐dependent operations on a daily basis. Blood and feces share many of the same dependencies, and feces may present a new opportunity for the blood services to handle. In this paper, we describe how an FMT service may be established and embedded within the blood service infrastructure, and we explain the benefits of using blood donors as feces donors. We further explore the current indications of FMT, the challenges related to the lack of legislation, and the future perspectives for blood banks to meet a new and increasing demand.