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Pathological investigation and viral antigen distribution of emerging African swine fever in Vietnam
Author(s) -
Izzati Uda Zahli,
Inanaga Minori,
Hoa Nguyen Thi,
Nueangphuet Phawut,
Myint Ohnmar,
Truong Quang Lam,
Lan Nguyen Thi,
Norimine Junzo,
Hirai Takuya,
Yamaguchi Ryoji
Publication year - 2021
Publication title -
transboundary and emerging diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.392
H-Index - 63
eISSN - 1865-1682
pISSN - 1865-1674
DOI - 10.1111/tbed.13851
Subject(s) - african swine fever virus , outbreak , virology , african swine fever , immunohistochemistry , antigen , biology , capsid , virus , peripheral blood mononuclear cell , pathology , immunology , medicine , biochemistry , in vitro
African swine fever (ASF) is emerging in Vietnam and poses a continuing severe threat to the swine industry. A histopathological study of clinical samples collected during the May to July 2019 outbreak of ASF was performed to determine the characteristic lesions. We analysed samples from eight ASFV‐infected farms. Histopathological results revealed the characteristic lesions of the acute to the subacute clinical form of ASF. Immunohistochemical results showed ASFV viral antigen distribution in mononuclear cells/macrophage in various organs, hepatocytes and renal tubular epithelium. Molecular analysis of partial capsid protein 72 gene revealed that ASFV strain from the eight separate outbreaks belonged to genotype II.