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We report two autopsy cases of severe fever with thrombocytopenia syndrome ( SFTS ) with a high fatality rate in aged  J apanese patients. Both cases were caused by a tick‐bite. The pathognomonic histological feature was necrotizing lymphadenitis of systemic lymphoid tissue with  SFTS  viruses and  SFTSV‐RNA  copies. Marked fungal infections were also observed in the lungs of both patients. Since cellular immune function may be suppressed in  SFTS  patients, physicians should be aware of possible fungal infections.

pathology international

Two autopsy cases of severe fever with thrombocytopenia syndrome ( SFTS ) in  J apan: A pathognomonic histological feature and unique complication of  SFTS