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Consensus recommendations for the use of retinoids in ichthyosis and other disorders of cornification in children and adolescents
Author(s) -
Zaenglein Andrea L.,
Levy Moise L.,
Stefanko Nicole S.,
Benjamin Latanya T.,
Bruckner Anna L.,
Choate Keith,
Craiglow Brittany G.,
DiGiovanna John J.,
Eichenfield Lawrence F.,
Elias Peter,
Fleckman Philip,
Lawley Leslie P.,
Lewis Richard A.,
Lucky Anne W.,
Mathes Erin F.,
Milstone Leonard M.,
Paller Amy S.,
Patel Sonali S.,
Siegel Dawn H.,
Teng Joyce,
Tanumihardjo Sherry A.,
Thaxton Lauren,
Williams Mary L.
Publication year - 2020
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/pde.14408
Subject(s) - medicine , ichthyosis , isotretinoin , acitretin , retinoid , dermatology , special populations , acne , psoriasis , psychology , psychotherapist , retinoic acid , biochemistry , gene , chemistry
Topical and systemic retinoids have long been used in the treatment of ichthyoses and other disorders of cornification. Due to the need for long‐term use of retinoids for these disorders, often beginning in childhood, numerous clinical concerns must be considered. Systemic retinoids have known side effects involving bone and eye. Additionally, potential psychiatric and cardiovascular effects need to be considered. Contraceptive concerns, as well as the additive cardiovascular and bone effects of systemic retinoid use with hormonal contraception must also be deliberated for patients of childbearing potential. The Pediatric Dermatology Research Alliance (PeDRA) Use of Retinoids in Ichthyosis Work Group was formed to address these issues and to establish best practices regarding the use of retinoids in ichthyoses based on available evidence and expert opinion.