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LBBAP in patients with normal intrinsic QRS duration: Electrical and mechanical characteristics
Author(s) -
Wang Shaoxian,
Lan Rongfang,
Zhang Ning,
Zheng Jia,
Gao Yuan,
Bai Jian,
Wu Xiang,
Xu Xinyue,
Wang Tianqi,
Xu Wei
Publication year - 2021
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/pace.14114
Subject(s) - medicine , qrs complex , ventricle , cardiology
Background Left bundle branch area pacing (LBBAP) is an innovative pacing technology, which needs further study. Methods Seventy LBBAP patients with intrinsic QRS duration (QRSd) less than 120 ms were consecutively enrolled in our center. According to whether the left bundle branch potential (LBBp) was recorded or not, the patients were divided into the potential positive group (LBBAP+) and the potential negative group (LBBAP−). Electrocardiographic and echocardiographic parameters were used to evaluate electrical and mechanical characteristics. Lead parameters and complications were followed‐up. Results There were 52 patients in LBBAP+ and 18 patients in LBBAP−. The QRSd and the left ventricular activation time (LVAT) were wider after LBBAP. QRSd showed no significant difference between LBBAP+ and LBBAP−. LVAT was significantly shorter in LBBAP+ than in LBBAP−. Frontal QRS axis shifted leftward and the V1 morphologies changed after LBBAP. QRS axis and V1 morphologies showed no significant differences between two groups. Paced R‐wave transition moved forward compared with intrinsic R‐wave transition in both groups. Peak systolic strain of left ventricle (LVPSS) increased, and peak systolic dispersion of left ventricle (LVPSD) did not change significantly after LBBAP. Systolic and diastolic function as well as mechanical synchronism had no significant differences between two groups. LBBAP had great pacing parameters. Conclusion LBBAP changes electrical and mechanical characteristics and has good safety in patients with normal intrinsic QRSd. LBBAP+ and LBBAP− show no significant differences in mechanical synchronization and interventricular electrical synchronization. The LBBAP+ shows better left ventricular electrical synchronicity.

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