English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

Summary  Plants have evolved powerful immune systems to recognize pathogens and avoid invasions, but the genetic basis of plant susceptibility is less well‐studied, especially to oomycetes, which cause disastrous diseases in many ornamental plants and food crops. In this research, we identified a negative regulator of plant immunity to the oomycete  Phytophthora parasitica ,  AtRTP5  ( Arabidopsis thaliana  Resistant to  Phytophthora  5), which encodes a WD40 repeat domain‐containing protein. The AtRTP5 protein, which was tagged with green fluorescent protein (GFP), is localized in the nucleus and plasma membrane. Both the  A. thaliana  T‐DNA insertion  rtp5  mutants and the  Nicotiana benthamiana RTP5  ( NbRTP5 ) silencing plants showed enhanced resistance to  P. parasitica , while overexpression of  AtRTP5  rendered plants more susceptible. The transcriptomic analysis showed that mutation of  AtRTP5  suppressed the biosynthesis of endogenous jasmonic acid (JA) and JA‐dependent responses. In contrast, salicylic acid (SA) biosynthesis and SA‐dependent responses were activated in the T‐DNA insertion mutant  rtp5‐3 . These results show that  AtRTP5  acts as a conserved negative regulator of plant immunity to  Phytophthora  pathogens by interfering with JA and SA signalling pathways.

molecular plant pathology

AtRTP5  negatively regulates plant resistance to  Phytophthora  pathogens by modulating the biosynthesis of endogenous jasmonic acid and salicylic acid