Open AccessTreatment of primary hyperparathyroidism in a Miniature Horse using chemical ablation of abnormal parathyroid tissue localized by 3‐phase computed tomography
Author(s) -
Colmer Sarah F.,
Wulster Kathryn,
Johnson Amy L.,
Levine David G.,
Underwood Claire,
Watkins Trevor W.,
Van Eps Andrew W.
Publication year - 2022
Publication title -
journal of veterinary internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 103
eISSN - 1939-1676
pISSN - 0891-6640
DOI - 10.1111/jvim.16390
Subject(s) - medicine , primary hyperparathyroidism , thyroid , parathyroid gland , parathyroid hormone , horse , scintigraphy , ablation , radiology , ultrasound , hyperparathyroidism , pathology , endocrinology , calcium , paleontology , biology
A 15‐year‐old Miniature Horse mare with persistently increased plasma calcium (total and ionized) and serum parathyroid hormone concentrations was presented for suspected primary hyperparathyroidism. Ultrasonography of the thyroid region identified an enlarged heterogeneous mass axial to the right thyroid lobe suggestive of an enlarged parathyroid gland, which was further confirmed using sestamibi nuclear scintigraphy and 3‐phase computed tomography. Percutaneous ultrasound‐guided ethanol ablation of the mass, a method not previously described in the horse, was performed under general anesthesia resulting in rapid normalization of plasma ionized calcium and serum parathyroid hormone concentrations. Ablation of abnormal parathyroid gland tissue may be a suitable alternative to surgical resection in certain cases of primary hyperparathyroidism in the horse.