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Background  Correlation of plasma fibrinogen concentration (fibrinogen Clauss ) with rotational thromboelastometry (ROTEM) parameters has not been investigated in dogs.    Objectives  To determine the correlation between plasma coagulation tests and fibrinogen Clauss  with ROTEM parameters and to evaluate their ability to predict bleeding in dogs.    Animals  Ninety‐seven dogs with concurrent determination of fibrinogen Clauss  and fibrin polymerization test (FIBTEM) analysis.    Methods  Signalment, pretreatment, clinical signs of bleeding, fibrinogen Clauss , plasma coagulation test results, hematocrit, platelet count, FIBTEM, extrinsic (EXTEM) and intrinsic (INTEM) activated ROTEM assays were retrieved retrospectively. Correlations between fibrinogen Clauss  and FIBTEM maximum clot firmness (MCF FIBTEM ) and between prothrombin time (PT) or activated partial thromboplastin time (aPTT) and ROTEM parameters were determined. Dogs were further assigned to groups with or without clinical signs of bleeding. The prognostic significance of significantly different parameters to predict bleeding was evaluated.    Results  Fibrinogen Clauss  showed strong correlation with MCF FIBTEM  (r = 0.860, n = 97,  P  < .001). PT showed strong correlation with EXTEM clotting time (CT EXTEM ) (r = 0.839, n = 53,  P  < .001), and aPTT was strongly correlated with INTEM CT (CT INTEM ) (r = 0.664, n = 31,  P  < .001). Platelet count, PT/aPTT, EXTEM clot formation time (CFT EXTEM ), MCF EXTEM , EXTEM maximum clot elasticity (MCE EXTEM ), and CT INTEM  were significantly different between groups. A CT INTEM  >149 seconds was 100% sensitive to detect bleeding.    Conclusions and Clinical Importance  The MCF FIBTEM  can be used to evaluate the effect of fibrinogen on hemostasis as an alternative to determination of fibrinogen Clauss . In addition, CT EXTEM  and CT INTEM  are strongly correlated with PT and aPTT, respectively.

Correlation of plasma coagulation tests and fibrinogen Clauss with rotational thromboelastometry parameters and prediction of bleeding in dogs