Open AccessSeizure occurrence in dogs under primary veterinary care in the UK: prevalence and risk factors
Author(s) -
Erlen Alexander,
Potschka Heidrun,
Volk Holger A.,
SauterLouis Carola,
O'Neill Dan G.
Publication year - 2018
Publication title -
journal of veterinary internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 103
eISSN - 1939-1676
pISSN - 0891-6640
DOI - 10.1111/jvim.15290
Subject(s) - medicine , epidemiology , breed , population , primary care , pediatrics , veterinary medicine , zoology , environmental health , family medicine , biology
Background Primary‐care veterinary clinical records can offer data to determine generalizable epidemiological data on seizures occurrence in the dog population. Objectives To identify and examine epidemiologic characteristics of seizure occurrence in dogs under primary veterinary care in the UK participating in the VetCompass™ Programme. Animals 455,553 dogs in VetCompass™’. Methods A cross‐sectional analysis estimated the 1‐year period prevalence and risk factors for dogs with seizures during 2013. Results The overall 1‐year period prevalence for dogs having at least one seizure during 2013 was 0.82% (95% CI 0.79‐0.84). Multivariable modelling identified breeds with elevated odd ratios [OR] compared with the Labrador Retriever (e.g. Pug OR: 3.41 95% CI 2.71‐4.28, P < 0.001). Males had higher risk for seizures (Male/Entire OR: 1.47 95% CI 1.30–1.66; Male/Neutered OR: 1.34 95% CI 1.19–1.51) compared to entire females. Age (3.00 ‐ ≤ 6.00 OR: 2.13 95% CI 1.90‐2.39, P < 0.001, compared to animals aged 0.50–≤ 3.00 years), and bodyweight (≥ 40.00kg, OR: 1.24 95% CI 1.08–1.41, P = 0.002, compared to animals weighing < 10.0 kg) were identified as risk factors for seizures. Conclusion and clinical Importance Seizures are a relatively common clinical finding in dogs. The results for breed, age, sex and bodyweight as risk factors can assist veterinarians in refining differential diagnosis lists for dogs reported with behaviors that may have been seizures. In addition, the prevalence values reported here can support pharmacovigilance with baseline data from the overall population.