Open AccessComputer tomographic imaging in 4 dogs with primary nasal canine transmissible venereal tumor and differing cellular phenotype
Author(s) -
Ojeda Javier,
Mieres Marcelo,
Soto Francisco,
Arnes Verónica,
Paredes Enrique,
Navarrete María
Publication year - 2018
Publication title -
journal of veterinary internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 103
eISSN - 1939-1676
pISSN - 0891-6640
DOI - 10.1111/jvim.15125
Subject(s) - medicine , pathology , nasal cavity , nose , stage (stratigraphy) , histopathological examination , phenotype , chemotherapy , computed tomographic , sex organ , nasal septum , computed tomography , surgery , chemistry , gene , paleontology , genetics , biology , biochemistry
Primary nasal canine transmissible venereal tumor (CTVT) without genital affection is uncommon. The aim of this report was to describe the primary nasal CTVT findings and CT staging in 4 dogs with different cytological phenotypes. Three male dogs and 1 bitch were evaluated for their chronic histories of sneezing, snoring, mucopurulent nasal discharge and nasal deformation. Cytological examination of nasal secretions suggested CTVT, confirmed by histopathological examination and LINE‐1/c‐myc. Males had the plasmacytoid phenotype of CTVT, and the bitch had the lymphocytoid phenotype. CTVT were staged based on the CT findings using modified Adams staging system. The bitch was classified as stage 1, 2 males were classified as stage 3 and 1 male as stage 4. All dogs had a complete tumoral remission after chemotherapy. Plasmacytoid phenotype was identified in cases with most important damage of the nasal cavity. However, the cytological type did not affect the response to chemotherapy.