English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

Background  Studies investigating the prevalence of vector‐borne pathogens in southern California dogs are limited. Occult infections might be misdiagnosed as idiopathic immune‐mediated disease.    Hypothesis/Objectives  (1) To determine the prevalence of vector‐borne pathogens in southern California dogs with compatible clinical findings using PCR and serologic panels and (2) to determine whether testing convalescent samples and repeating PCR on acute samples using the same and different gene targets enhance detection.    Animals  Forty‐two client‐owned dogs with clinical signs of vector‐borne disease presenting to specialty practices in San Diego County.    Methods  Combined prospective and retrospective observational study. Forty‐two acute and 27 convalescent samples were collected. Acute samples were prospectively tested for antibodies to  Rickettsia, Ehrlichia, Bartonella, Babesia, Borrelia, and Anaplasma species . PCR targeting  Ehrlichia ,  Babesia ,  Anaplasma , hemotropic  Mycoplasma,  and  Bartonella  species was also performed. Retrospectively, convalescent samples were tested for the same organisms using serology, and for  Ehrlichia ,  Babesia ,  Anaplasma , and  Bartonella  species using PCR. Acute samples were retested using PCR targeting  Ehrlichia  and  Babesia  species.    Results  Evidence of exposure to or infection with a vector‐borne pathogen was detected in 33% (14/42) of dogs.  Ehrlichia  and  Babesia  species were most common; each was identified in 5 dogs. Convalescent serologic testing, repeating PCR, and using novel PCR gene targets increased detection by 30%.    Conclusions and Clinical Importance  Repeated testing using serology and PCR enhances detection of infection by vector‐borne pathogens in dogs with clinical signs of immune‐mediated disease. Larger prevalence studies of emerging vector‐borne pathogens in southern California dogs are warranted.

Prevalence of Vector‐Borne Pathogens in Southern California Dogs With Clinical and Laboratory Abnormalities Consistent With Immune‐Mediated Disease