Open AccessMitral Annular Plane Systolic Excursion and Tricuspid Annular Plane Systolic Excursion in Cats with Hypertrophic Cardiomyopathy
Author(s) -
Spalla I.,
Payne J.R.,
Borgeat K.,
Pope A.,
Fuentes V. Luis,
Connolly D.J.
Publication year - 2017
Publication title -
journal of veterinary internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 103
eISSN - 1939-1676
pISSN - 0891-6640
DOI - 10.1111/jvim.14697
Subject(s) - medicine , hypertrophic cardiomyopathy , asymptomatic , cardiology , cats , heart failure
Background Left ventricular ( LV ) systolic dysfunction is associated with increased risk of death in cats with hypertrophic cardiomyopathy ( HCM ). Mitral and tricuspid annular plane systolic excursion ( MAPSE and TAPSE , respectively) are measures of longitudinal systolic function and are reduced in human patients with HCM . Hypotheses Cats with HCM have lower MAPSE and TAPSE compared to control cats; lower MAPSE and TAPSE are associated with the presence of congestive heart failure ( CHF ) and reduced survival time. Animals 64 cats with HCM and 27 healthy cats. Forty‐five cats with HCM were not showing clinical signs, and 19 had CHF . Methods Retrospective study. Anatomic M‐mode from the left apical 4‐chamber view was used to record MAPSE from the free wall ( MAPSE FW ) and septum ( MAPSE IVS ) and TAPSE . Results Compared to controls, cats with HCM had lower MAPSE IVS (controls 5.2 [4.6–5.6] mm, asymptomatic HCM 4.7 [4.1–5.2] mm, HCM with CHF 2.6 [2.5–3.2] mm, P < .001), MAPSE FW (controls 5.9 [5.3–6.2] mm, asymptomatic HCM 4.7 [4.1–5.1] mm, HCM with CHF 2.8 [2.4–3.2] mm) and TAPSE (controls 8.6 [7.4–10.2] mm, asymptomatic HCM 7.2 [6.3–8.2] mm, HCM with CHF 4.6 [4.1–5.4] mm), with the lowest in the CHF group. Univariate survival analysis showed a shorter survival in cats displaying lower MAPSE IVS , MAPSE FW , and TAPSE . Conclusions and Clinical Importance MAPSE and TAPSE were lower in cats with HCM than in control cats and were lowest in CHF , suggesting that systolic longitudinal dysfunction is present in cats with HCM . MAPSE and TAPSE have potential prognostic significance.