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Background  In human medicine, right ventricular ( RV ) functional parameters represent a tool for risk stratification in patients with congestive heart failure caused by left heart disease. Little is known about  RV  alterations in dogs with left‐sided cardiac disorders.    Objectives  To assess  RV  and left ventricular ( LV ) function in dogs with myxomatous mitral valve disease ( MMVD ) with or without pulmonary hypertension ( PH ).    Animals  One‐hundred and fourteen dogs: 28 healthy controls and 86 dogs with  MMVD  at different stages.    Methods  Prospective observational study. Animals were classified as healthy or having  MMVD  at different stages of severity and according to presence or absence of  PH . Twenty‐eight morphological, echo‐ D oppler, and tissue  D oppler imaging ( TDI ) variables were measured and comparison among groups and correlations between  LV  and  RV  parameters were studied.    Results  No differences were found among groups regarding  RV  echo‐ D oppler and  TDI  variables. Sixteen significant correlations were found between  RV TDI  and left heart echocardiographic variables. Dogs with  PH  had significantly higher transmitral  E  wave peak velocity and higher  E /eʹ ratio of septal (s MV ) and lateral (p MV ) mitral annulus. These 2 variables were found to predict presence of  PH  with a sensitivity of 84 and 72%, and a specificity of 71 and 80% at cut‐off values of 10 and 9.33 for s MV E /eʹ and p MV E /eʹ, respectively.    Conclusions and clinical importance  No association between variables of  RV  function and different  MMVD  stage and severity of  PH  could be detected. Some relationships were found between echocardiographic variables of right and left ventricular function.

journal of veterinary internal medicine

Utility of Tissue  D oppler Imaging in the Echocardiographic Evaluation of Left and Right Ventricular Function in Dogs with Myxomatous Mitral Valve Disease with or without Pulmonary Hypertension