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Non‐invasive imaging in dermatology and the unique potential of raster‐scan optoacoustic mesoscopy
Author(s) -
Hindelang B.,
Aguirre J.,
Schwarz M.,
Berezhnoi A.,
Eyerich K.,
Ntziachristos V.,
Biedermann T.,
Darsow U.
Publication year - 2019
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/jdv.15342
Subject(s) - medicine , raster scan , medical imaging , medical physics , molecular imaging , radiology , artificial intelligence , computer science , microbiology and biotechnology , biology , in vivo
In recent years, several non‐invasive imaging methods have been introduced to facilitate diagnostics and therapy monitoring in dermatology. The microscopic imaging methods are restricted in their penetration depth, while the mesoscopic methods probe deeper but provide only morphological, not functional, information. ‘Raster‐scan optoacoustic mesoscopy’ ( RSOM ), an emerging new imaging technique, combines deep penetration with contrast based on light absorption, which provides morphological, molecular and functional information. Here, we compare the capabilities and limitations of currently available dermatological imaging methods and highlight the principles and unique abilities of RSOM . We illustrate the clinical potential of RSOM , in particular for non‐invasive diagnosis and monitoring of inflammatory and oncological skin diseases.