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A case of polyneuropathy associated with diabetic ketoacidosis in new‐onset type 1 diabetes
Author(s) -
Sada Kokoro,
Hidaka Shuji,
Takemaru Makoto,
Ueno Daisuke,
Shibata Hirotaka
Publication year - 2022
Publication title -
journal of diabetes investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.089
H-Index - 50
eISSN - 2040-1124
pISSN - 2040-1116
DOI - 10.1111/jdi.13724
Subject(s) - medicine , diabetic ketoacidosis , diabetes mellitus , polyneuropathy , type 1 diabetes , complication , context (archaeology) , diabetic neuropathy , paralysis , surgery , endocrinology , paleontology , biology
Although diabetic peripheral neuropathy is the most common diabetic microangiopathic complication, several other neuropathy syndromes can occur in the context of diabetes. We describe a rare case of polyneuropathy associated with diabetic ketoacidosis in a patient with new‐onset type 1 diabetes. A 42‐year‐old man with diabetic ketoacidosis was admitted to our hospital with complications of respiratory and renal failure requiring mechanical ventilation and hemodialysis, respectively. After diabetic ketoacidosis improved from the critical state, he developed upper‐ and lower‐limb paralysis with sensory disturbances and pain, as well as right facial paralysis, left recurrent nerve paralysis, and left hypoglossal nerve paralysis. Autonomic nerve function was also impaired. As the pathophysiology, prevention, and treatment of polyneuropathy associated with diabetic ketoacidosis are unclear, the neurologic function of patients with diabetic ketoacidosis should be closely monitored.

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