Open AccessThe early diagnostic value of ankle‐brachial index combined with feet electrochemical skin conductance for peripheral artery disease in type 2 diabetes
Author(s) -
Zhao Yun,
Huang Liji,
Zhou Xiqiao,
Liu Jingshun,
Yu Jiangyi
Publication year - 2022
Publication title -
journal of diabetes investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.089
H-Index - 50
eISSN - 2040-1124
pISSN - 2040-1116
DOI - 10.1111/jdi.13687
Subject(s) - medicine , peripheral , logistic regression , diabetes mellitus , arterial disease , ankle , type 2 diabetes , type 2 diabetes mellitus , cardiology , disease , peripheral neuropathy , predictive value , gastroenterology , surgery , vascular disease , endocrinology
Aims/Introduction In this paper, we focused on exploring the diagnostic and predictive clinical utility of ankle‐brachial index (ABI) in combination with feet electrochemical skin conductance (FESC) for peripheral artery disease (PAD) in Chinese patients with type 2 diabetes mellitus (T2DM). Materials and Methods Overall, 183 Chinese T2DM patients were enrolled in this study. The patients were classified into three groups: Group 1 comprised of uncomplicated type 2 diabetics ( n = 36), Group 2 consisted of patients with diabetic peripheral neuropathy ( n = 103) whereas Group 3 patients displayed peripheral artery disease ( n = 44). All patients underwent Sudoscan test using a Sudoscan (Paris, France) and ABI assessment. Results Multivariate logistic regression models revealed that FESC was an independent risk factor of developing PAD in patients with type 2 diabetes. The AUC for diagnostic, positive predictive and negative predictive value of ABI in combination with FESC for PAD were 0.907, 0.733 and 0.920, respectively. The specificity and sensitivity of ABI in combination with FESC for PAD were 0.914 and 0.750, respectively. Conclusions Ankle‐brachial index in combination with FESC can accurately be used in early diagnosis of PAD.