Open AccessFighting the uphill battle to cure type 1 diabetes
Author(s) -
Lee Eun Young,
Yoon KunHo
Publication year - 2021
Publication title -
journal of diabetes investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.089
H-Index - 50
eISSN - 2040-1124
pISSN - 2040-1116
DOI - 10.1111/jdi.13613
Subject(s) - medicine , type 1 diabetes , beta cell , diabetes mellitus , islet , type 2 diabetes , beta (programming language) , insulin , artificial pancreas , immunotherapy , immune system , immunology , bioinformatics , endocrinology , computer science , biology , programming language
Three complementary approaches for type 1 diabetes. Immunotherapy targets the pathogenic immune cells or inflammatory cytokines to revert type 1 diabetes. An artificial pancreas delivers insulin automatically using continuous glucose monitoring, a controlling algorithm, and an insulin pump. Beta cell replacement therapy varies depending on the cell sources: allogeneic, or xenogeneic islet; beta‐like cells derived from ESCs or iPSCs.