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T helper 17 cells: A new actor on the stage of type 2 diabetes and aging?
Author(s)
-
Chang YiCheng
,
Hee SiowWey
,
Chuang LeeMing
Publication year
-
2021
Publication title
-
journal of diabetes investigation
Language(s)
-
English
Resource type
-
Journals
SCImago Journal Rank
-
1.089
H-Index
-
50
eISSN
-
2040-1124
pISSN
-
2040-1116
DOI
-
10.1111/jdi.13541
Subject(s)
-
autophagy , medicine , metformin , type 2 diabetes , inflammation , immune system , diabetes mellitus , immunology , gerontology , endocrinology , apoptosis , biology , biochemistry
Metformin improves mitochondrial function and enhances autophagy of T helper 17 cells, leading to decreased inflammation. This highlights the importance of metabolic modulation of immune cells.
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