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T helper 17 cells: A new actor on the stage of type 2 diabetes and aging?
Author(s) -
Chang YiCheng,
Hee SiowWey,
Chuang LeeMing
Publication year - 2021
Publication title -
journal of diabetes investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.089
H-Index - 50
eISSN - 2040-1124
pISSN - 2040-1116
DOI - 10.1111/jdi.13541
Subject(s) - autophagy , medicine , metformin , type 2 diabetes , inflammation , immune system , diabetes mellitus , immunology , gerontology , endocrinology , apoptosis , biology , biochemistry
Metformin improves mitochondrial function and enhances autophagy of T helper 17 cells, leading to decreased inflammation. This highlights the importance of metabolic modulation of immune cells.

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