Open AccessDoes the breakdown of the detoxification system for aldehydes as a result of aldose reductase upregulation lead to alcohol‐induced liver injury in humans and mice?
Author(s) -
Hotta Nigishi,
Kawamura Takahiko,
Umemura Toshitaka
Publication year - 2020
Publication title -
journal of diabetes investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.089
H-Index - 50
eISSN - 2040-1124
pISSN - 2040-1116
DOI - 10.1111/jdi.13305
Subject(s) - polyol pathway , aldose reductase , medicine , alcoholic liver disease , cirrhosis , insulin resistance , liver injury , detoxification (alternative medicine) , fatty liver , chronic liver disease , diabetes mellitus , liver disease , steatosis , pathogenesis , endocrinology , disease , pathology , alternative medicine