Open AccessResponse to insulin degludec and insulin glargine 300 U/mL: Which of these two insulins causes less hypoglycemia?
Author(s) -
Yamabe Mizuho
Publication year - 2019
Publication title -
journal of diabetes investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.089
H-Index - 50
eISSN - 2040-1124
pISSN - 2040-1116
DOI - 10.1111/jdi.13145
Subject(s) - insulin degludec , insulin glargine , medicine , hypoglycemia , metformin , insulin , diabetes mellitus , endocrinology
To minimize the influence of possible confounding factors, the study was carried out in a cross‐over manner. Using flash glucose monitoring, insulin glargine 300 U/mL showed less nocturnal hypoglycemia than insulin degludec 100 U/mL . Examination of insulin degludec 100 U/mL nocturnal hypoglycemia by combined oral medications suggested that metformin combination might be the cause of nocturnal hypoglycemia.