Open AccessGlutaminostatin: Another facet of glucagon as a regulator of plasma amino acid concentrations
Author(s) -
Hayashi Yoshitaka
Publication year - 2019
Publication title -
journal of diabetes investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.089
H-Index - 50
eISSN - 2040-1124
pISSN - 2040-1116
DOI - 10.1111/jdi.13110
Subject(s) - glucagon , incretin , medicine , endocrinology , diabetes mellitus , glutamine , glucagon receptor , islet , insulin , amino acid , chemistry , type 2 diabetes , biochemistry
Glucagon plays an essential role in robust feedback regulation between the liver and α‐cells, and exerts suppressive or static effects on the plasma concentration of amino acids, especially glutamine. Thereby, “glutaminostatin” might be an alternative name in recognition of another facet of glucagon as a suppressor of plasma glutamine levels.