Open AccessNeuronatin and glucose‐induced stress in pancreatic β‐cells
Author(s) -
Asahara Shunichiro
Publication year - 2019
Publication title -
journal of diabetes investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.089
H-Index - 50
eISSN - 2040-1124
pISSN - 2040-1116
DOI - 10.1111/jdi.12993
Subject(s) - endoplasmic reticulum , medicine , association (psychology) , stress (linguistics) , pathological , promotion (chess) , diabetes mellitus , insulin , neuroscience , bioinformatics , endocrinology , microbiology and biotechnology , psychology , biology , psychotherapist , political science , linguistics , philosophy , politics , law
Recently, reports have described the association between neuronatin ( Nnat ) and endoplasmic reticulum stress, and the promotion of insulin processing by Nnat , the expression of which is greatly induced by glucose stimulation. The roles of Nnat are worthy of note under both physiological and pathological conditions. In this Commentary, I discuss the association between Nnat and glucose‐induced stress on the basis of recent knowledge.