Open AccessHuman glomerular transcriptome of diabetic kidneys: Can the podocyte cytoskeleton be a therapeutic target?
Author(s) -
Maezawa Yoshiro,
Yokote Koutaro
Publication year - 2019
Publication title -
journal of diabetes investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.089
H-Index - 50
eISSN - 2040-1124
pISSN - 2040-1116
DOI - 10.1111/jdi.12951
Subject(s) - diabetic nephropathy , albuminuria , podocyte , medicine , diabetes mellitus , transcriptome , nephrology , nephropathy , microarray analysis techniques , renal function , bioinformatics , gene expression , endocrinology , biology , kidney , gene , proteinuria , genetics
Diabetic nephropathy is the leading cause of end stage renal failure in Japan. Clarification of its detailed pathogenesis and development of therapeutic methods are urgent issues. In this article in the Journal of the American Society of Nephrology, Pan et al.[1] showed a usefulness of weighted gene co-expression network analysis (WGCNA) and identified a potentially important candidate molecules that regulate diabetic nephropathy. This article is protected by copyright. All rights reserved.