English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

Aims/Introduction  To investigate the effect of endurance training on hippocampus  DJ ‐1 and cannabinoid receptor type 2 ( CB  2 ) protein and blood glucose concentration in diabetic rats.    Materials and Methods  A total of 32 rats were randomly divided into diabetic (D), diabetic and exercise ( DE ), exercise (E) and control (C) groups. The endurance training was carried out five times per week for 6 weeks. The hippocampus  DJ ‐1 and  CB  2  were measured using an enzyme‐linked immunosorbent assay method.    Results  The level of  DJ ‐1 in the D group was significantly higher than the other groups ( P  ≤ 0.01). However, the level of  DJ ‐1 was not significantly different between the C, E and  DE  groups. In addition, the level of  CB  2  was significantly lower in the D group compared with the other groups ( P  ≤ 0.01). Blood glucose was significantly higher in the D group compared with the  DE  group ( P  ≤ 0.05). Furthermore, a significant positive correlation between the level of  DJ ‐1 and blood glucose was observed ( r  = 0.67,  P  ≤ 0.001). There was also a significant inverse correlation between the level of  CB  2  and blood glucose ( r  = −0.77,  P  ≤ 0.001).    Conclusions  The results of this study suggest that the level of  DJ ‐1 and  CB  2  might change in response to diabetes, and regular aerobic exercise could mediate the effect of  DJ ‐1 and  CB  2  on diabetes‐induced neurodegenerative diseases.

Effects of endurance training on hippocampus DJ ‐1, cannabinoid receptor type 2 and blood glucose concentration in diabetic rats