Open AccessCase of lipoatrophic diabetes induced by juvenile dermatomyositis
Author(s) -
Baba Yusuke,
Kaneko Hiyori,
Takemoto Minoru,
Ide Kana,
Haga Yuki,
Kanda Tatsuo,
Akita Shinsuke,
Kubota Yoshitaka,
Kuroda Masayuki,
Kitagawa Yutaka,
Yokote Koutaro
Publication year - 2018
Publication title -
journal of diabetes investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.089
H-Index - 50
eISSN - 2040-1124
pISSN - 2040-1116
DOI - 10.1111/jdi.12745
Subject(s) - juvenile dermatomyositis , medicine , diabetes mellitus , rosiglitazone , dermatomyositis , pioglitazone , endocrinology , type 2 diabetes
Lipodystrophy is a rare condition that is often accompanied by one or more metabolic diseases. Here, we report a case of lipoatrophic diabetes induced by juvenile dermatomyositis. Although pioglitazone was not effective for lowering blood glucose levels, our observation suggested that it improved liver function slightly. The effectiveness of metreleptin for lowering blood glucose levels could not be determined, as we administered it in a short period. Liver biopsy showed burned‐out non‐alcoholic steatohepatitis. The present results show that the successful treatment of lipoatrophic diabetes induced by juvenile dermatomyositis requires an early diagnosis and therapeutic intervention.