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Aims/Introduction  Carotid intima‐media thickness ( CIMT ) is an established predictor of cardiovascular disease and stroke. We aimed to identify the association between  CIMT  and blood glucose, as well as the risk factors associated with increased  CIMT  in a low‐income Chinese population.    Materials and Methods  Stroke‐free and cardiovascular disease‐free residents aged ≥45 years were recruited. B‐mode ultrasonography was carried out to measure  CIMT .    Results  There were 2,643 participants (71.0%) in the normal group, 549 (14.7%) in the impaired fasting glucose group and 533 (14.3%) in the diabetes mellitus group. The determinants of increased  CIMT  were older age; male sex; low education; hypertension; smoking; high levels of systolic blood pressure, fasting blood glucose and low‐density lipoprotein cholesterol; and low levels of diastolic blood pressure, triglycerides and high‐density lipoprotein cholesterol, after adjusting for covariates. Age and hypertension were the common risk factors for increased  CIMT  in all three groups. Furthermore, male sex, smoking and high low‐density lipoprotein cholesterol level were positively associated with the mean  CIMT  in the normal group; high triglycerides levels were negatively associated with the mean  CIMT  in the impaired fasting glucose group; and alcohol consumption was an independent risk factor for mean  CIMT  in the diabetes mellitus group. Hypertension was the greatest risk factor for increased  CIMT .    Conclusions  These findings suggest that it is crucial to manage and control traditional risk factors in low‐income populations in China in order to decelerate the recent dramatic increase in stroke incidence, and to reduce the burden of stroke.

journal of diabetes investigation

Association between carotid intima‐media thickness and fasting blood glucose level: A population‐based cross‐sectional study among low‐income adults in rural China