Open AccessWhere does liver fat go? A possible molecular link between fatty liver and diabetes
Author(s) -
Kikuchi Akihiro,
Takamura Toshinari
Publication year - 2017
Publication title -
journal of diabetes investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.089
H-Index - 50
eISSN - 2040-1124
pISSN - 2040-1116
DOI - 10.1111/jdi.12573
Subject(s) - medicine , fatty liver , diabetes mellitus , bioinformatics , endocrinology , disease , biology
An elevation of fatty acid delivery amplifies the TCA cycle flux with a rise in anaplerosis/cataplerosis, leading to a proportional rise in oxidative stress and inflammation in liver.