Open AccessSalt and sugar: Bad company
Author(s) -
Wada Jun
Publication year - 2017
Publication title -
journal of diabetes investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.089
H-Index - 50
eISSN - 2040-1124
pISSN - 2040-1116
DOI - 10.1111/jdi.12553
Subject(s) - medicine , adiponectin , endocrinology , adiponectin receptor 1 , adipose tissue , protein kinase a , diabetes mellitus , insulin resistance , biology , kinase , microbiology and biotechnology
This report shed light to unrecognized mechanism for the hyperglycemia‐induced sodium retention. The activation of PPAR?, elevation of serum adiponectin, and subsequent inhibition of SGLT2 may lead to natriuresis and glycosuria and it may be beneficial in hypertensive diabetic patients.