Open AccessPhotoreceptors in diabetic retinopathy
Author(s) -
Kern Timothy S,
Berkowitz Bruce A
Publication year - 2015
Publication title -
journal of diabetes investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.089
H-Index - 50
eISSN - 2040-1124
pISSN - 2040-1116
DOI - 10.1111/jdi.12312
Subject(s) - medicine , diabetic retinopathy , diabetes mellitus , ophthalmology , optometry , endocrinology
Although photoreceptors account for most of the mass and metabolic activity of the retina, their role in the pathogenesis of diabetic retinopathy has been largely overlooked. Recent studies suggest that photoreceptors might play a critical role in the diabetes‐induced degeneration of retinal capillaries, and thus can no longer be ignored. The present review summarizes diabetes‐induced alterations in photoreceptor structure and function, and provides a rationale for further study of a role of photoreceptors in the pathogenesis of the retinopathy.