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Aims/Introduction  Microalbuminuria is positively related to metabolic syndrome (MetS). Our aim was to investigate whether urinary albumin‐to‐creatinine ratio ( UACR ) within the normal range is independently associated with MetS in Chinese community‐based patients with type 2 diabetes.    Materials and Methods  A total of 514 participants (206 males and 308 females; mean age 66 years) with  UACR  less than 3.5 mg/mmol were enrolled from two downtown areas of Shanghai. The participants were stratified into quartiles according to  UACR  levels. The prevalence of MetS was assessed and compared among the four groups by binary logistic regression.    Results  Compared with participants with  UACR s in the first quartile, the other quartiles had a higher prevalence of MetS (65.9%, 74.4% and 81.3%, respectively,  P  = 0.001) after adjustment for sex and age. After adjusting for potential confounders, participants in the second to the fourth quartile group had a 1.36‐, 1.84‐ and 2.73‐fold risk of MetS, respectively, relative to those in the lowest quartile. Furthermore,  UACR , whether as quartile groups or as a continuous variable, is an independent predictor of MetS after fully adjusting for other variables.    Conclusions  These results suggest that  UACR  even within the normal range is independently associated with MetS in Chinese community‐based patients with type 2 diabetes mellitus.

journal of diabetes investigation

High‐normal urinary albumin‐to‐creatinine ratio is independently associated with metabolic syndrome in  C hinese patients with type 2 diabetes mellitus: A cross‐sectional community‐based study