Open AccessMetformin as an anticancer drug: A Commentary on the metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides
Author(s) -
Song InSung,
Han Jin,
Lee Hong Kyu
Publication year - 2015
Publication title -
journal of diabetes investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.089
H-Index - 50
eISSN - 2040-1124
pISSN - 2040-1116
DOI - 10.1111/jdi.12300
Subject(s) - medicine , metformin , diabetes mellitus , drug , cancer , insulin sensitivity , pharmacology , sensitivity (control systems) , oncology , bioinformatics , endocrinology , insulin resistance , biology , electronic engineering , engineering
Metformin is widely used antidiabetic drug and also shows anticancer effect. As cancers arise more frequently in subjects with diabetes, knowledge on its effects on cancer metabolism might improve the treatment of diabetes.