Open AccessHigh prevalence of masked uncontrolled morning hypertension in elderly non‐valvular atrial fibrillation patients: Home blood pressure substudy of the ANAFIE Registry
Author(s) -
Kario Kazuomi,
Hasebe Naoyuki,
Okumura Ken,
Yamashita Takeshi,
Akao Masaharu,
Atarashi Hirotsugu,
Ikeda Takanori,
Koretsune Yukihiro,
Shimizu Wataru,
Tsutsui Hiroyuki,
Toyoda Kazunori,
Hirayama Atsushi,
Yasaka Masahiro,
Yamaguchi Takenori,
Teramukai Satoshi,
Kimura Tetsuya,
Kaburagi Jumpei,
Takita Atsushi,
Inoue Hiroshi
Publication year - 2021
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/jch.14095
Subject(s) - medicine , morning , blood pressure , atrial fibrillation , cardiology , masked hypertension , evening , diabetes mellitus , ambulatory blood pressure , endocrinology , physics , astronomy
In the ANAFIE Registry home blood pressure subcohort, we evaluated 5204 patients aged ≥75 years with non‐valvular atrial fibrillation (NVAF) to assess blood pressure (BP) control, prevalence of masked hypertension, and anticoagulant use. Mean clinic (C) and home (H) systolic/diastolic BP(SBP/DBP) was 128.5/71.3 and 127.7/72.6 mm Hg, respectively. Overall, 77.5% of patients had hypertension; of these, 27.7%, 13.4%, 23.4%, and 35.6% had well‐controlled, white coat, masked, and sustained hypertension, respectively. Masked hypertension prevalence increased with diabetes, decreased renal function, age ≥80 years, current smoker status, and chronic obstructive pulmonary disease. By morning/evening average, 59.0% of patients had mean H‐SBP ≥ 125 mm Hg; 48.9% had mean C‐SBP ≥ 130 mm Hg. Early morning hypertension (morning H‐SBP ≥ 125 mm Hg) was found in 65.9% of patients. Although 51.1% of patients had well‐controlled C‐SBP, 52.5% of these had uncontrolled morning H‐SBP. In elderly NVAF patients, morning H‐BP was poorly controlled, and masked uncontrolled morning hypertension remains significant.