Open AccessFructose Containing Sugars Do Not Raise Blood Pressure or Uric Acid at Normal Levels of Human Consumption
Author(s) -
Angelopoulos Theodore J.,
Lowndes Joshua,
Sinnett Stephanie,
Rippe James M.
Publication year - 2015
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/jch.12457
Subject(s) - fructose , medicine , hyperuricemia , sucrose , uric acid , blood pressure , sugar , food science , blood sugar , high fructose corn syrup , carbohydrate , corn syrup , endocrinology , chemistry , diabetes mellitus
The impact of fructose, commonly consumed with sugars by humans, on blood pressure and uric acid has yet to be defined. A total of 267 weight‐stable participants drank sugar‐sweetened milk every day for 10 weeks as part of their usual, mixed‐nutrient diet. Groups 1 and 2 had 9% estimated caloric intake from fructose or glucose, respectively, added to milk. Groups 3 and 4 had 18% of estimated caloric intake from high fructose corn syrup or sucrose, respectively, added to the milk. Blood pressure and uric acid were determined prior to and after the 10‐week intervention. There was no effect of sugar type on either blood pressure or uric acid (interaction P >.05), and a significant time effect for blood pressure was noted ( P <.05). The authors conclude that 10 weeks of consumption of fructose at the 50th percentile level, whether consumed as pure fructose or with fructose‐glucose–containing sugars, does not promote hyperuricemia or increase blood pressure.