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Evaluation of 65% Permethrin Spot‐on and Deltamethrin‐impregnated Collars for Canine Leishmania infantum Infection Prevention
Author(s) -
Ferroglio E.,
Poggi M.,
Trisciuoglio A.
Publication year - 2008
Publication title -
zoonoses and public health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.87
H-Index - 65
eISSN - 1863-2378
pISSN - 1863-1959
DOI - 10.1111/j.1863-2378.2007.01092.x
Subject(s) - leishmania infantum , permethrin , deltamethrin , seroconversion , veterinary medicine , leishmaniasis , biology , medicine , virology , immunology , visceral leishmaniasis , antibody , pesticide , agronomy
Summary During the 2004 and 2005 sand fly seasons, we evaluated the efficacy of a 65% spot‐on solution of permethrin (Exspot, Schering & Plough) and deltamethrin‐impregnated collar (Scalibor, Intervet) in reducing Leishmania infantum infection, in a canine leishmaniasis (CanL) endemic region (Liguria) in Italy. Immunofluorescent assay (IFA) revealed that three of 120 dogs (2.5%) treated with a 65% spot‐on solution of permethrin, as three of 119 dogs (2.5%) treated with deltamethrin‐impregnated collar have shown seroconversion after sand fly season. On the contrary, seroconversion was 15% in 188 untreated control dogs. Treatment reduced the risk of infection by 84%. The difference in treated dogs and control ones is highly significant (χ 2 = 12.4; P = 0.0004). Our results show that treatment with 65% spot‐on solution of permethrin and the deltamethrin‐impregnated collar are effective in reducing the risk of acquiring L. infantum infection.