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Successful in Vitro Fertilization with Sperm Cells from a Man with Immune Infertility
Author(s) -
NAAKTGEBOREN N.,
DEVROEY P.,
STEIRTEGHEM A.C.
Publication year - 1985
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1985.tb37533.x
Subject(s) - in vitro fertilisation , infertility , andrology , sperm , insemination , gynecology , human fertilization , pregnancy , medicine , embryo transfer , abortion , obstetrics , biology , genetics , anatomy
In vitro fertilization and embryo transfer was carried out in a couple that has been infertile for 7 years. High titers of antisperm autoantibodies in the husband's serum are (table, see text) believed to be the main cause of their infertility. Prolonged methylprednisolone treatment of the man combined with artificial insemination remained unsuccessful. In two IVF attempts embryos were obtained and replaced using capacitated sperm of the husband. A pregnancy was established in the second IVF cycle, but a spontaneous abortion followed after 6 weeks of amenorrhea.

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