Premium
Association study of polymorphisms within matrix metalloproteinase 9 with bronchial asthma
Author(s) -
Ganter K.,
Deichmann K. A.,
Heinzmann A.
Publication year - 2005
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.2005.00516.x
Subject(s) - asthma , matrix metalloproteinase , matrix metalloproteinase 9 , medicine , population , gene , immunology , genetics , biology , environmental health
Summary Matrix metalloproteinase 9 plays an important role in the development of bronchial asthma. We were interested in whether the polymorphisms –T1702A, –C1562T, R279Q and +C6T within the matrix metalloproteinase 9 ( MMP‐9 ) gene were associated with asthma in a population of 231 asthmatic children. However, we found no association. Thus MMP‐9 might not be a major gene for asthma.