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ATP‐ase positive cells in human oral mucosa transplanted to nude mice
Author(s) -
DABELSTEEN ERIK,
KIRKEBY SVEND
Publication year - 1981
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1981.tb01704.x
Subject(s) - oral mucosa , transplantation , microbiology and biotechnology , biology , cancer research , chemistry , medicine , pathology
– A model to study the differentiation of human oral epithelium in vivo utilizing transplantation of human tissue to nude mice has been described. Previous studies have described the epithelia cells in this kmodel. In this study we demonstrate that 8 d after transplantation, Langerhans cells, identified as ATP‐ase positive dendritic cells, have almost disappeared from the transplanted epithelium whereas at day 21 after transplantation such cells were abundant. It is suggested that the ATP‐ase positive cells which reappear in the transplanted epithelium are of mouse origin.