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Primary small cell carcinoma of the nasal cavity with an unusual oral manifestation
Author(s) -
Tarozzi Marco,
Demarosi Federica,
Lodi Giovanni,
Sardella Andrea,
Carrassi Antonio
Publication year - 2007
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.2007.00486.x
Subject(s) - medicine , hard palate , malignancy , nasal cavity , radiation therapy , chemotherapy , pathology , carcinoma , lesion , lung , lymphatic system , oral cavity , immunohistochemistry , small cell carcinoma , tongue , radiology , surgery , orthodontics
Small cell carcinoma (SCC) is a malignancy that mainly occurs in the lung, with primary lesions in the head and neck being very rare. This neoplasm has an aggressive growth pattern, high recurrence rate, and tendency to metastasize to other sites via the lymphatics and bloodstream. The prognosis of patients with SCC is poor, as the 5‐year survival is only 13%. Treatment options include surgical excision, multiple‐agent chemotherapy, and radiation therapy. We report a rare case of primary SCC of the nasal cavity presenting as a lesion of the hard palate and describe its clinical, histologic, and immunohistochemical features.