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Cerebrospinal fluid enzymes in neurological diseases
Author(s) -
Stensland E.,
Sandberg S.,
Berge R.,
Aarli J. A.,
Romslo I.
Publication year - 1981
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1981.tb00748.x
Subject(s) - cerebrospinal fluid , creatine kinase , lactate dehydrogenase , adenylate kinase , medicine , enzyme , neurology , pathology , biochemistry , chemistry , psychiatry , receptor
The activities of adenylate kinase, creatine kinase and lactate dehydrogenase were measured in cerebrospinal fluid and serum from 127 patients admitted to the Department of Neurology. All cerebrospinal fluid samples with hemoglobin > 1 mg/1 were excluded. Upper reference limits for the enzyme determinations were established, using samples from patients without objective criteria of organic involvement of the nervous system. High enzyme activities did not correlate to any particular group of diseases and were also found in patients without organic brain diseases. We conclude that determination of the three enzymes in cerebrospinal fluid is of limited value in the diagnosis of neurological diseases.