Open AccessTissue cultures from adult human postmortem subcortical brain areas
Author(s) -
Verwer R.W.H.,
Dubelaar E.J.G.,
Hermens W.T.J.M.C.,
Swaab D.F.
Publication year - 2002
Publication title -
journal of cellular and molecular medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.44
H-Index - 130
eISSN - 1582-4934
pISSN - 1582-1838
DOI - 10.1111/j.1582-4934.2002.tb00522.x
Subject(s) - human brain , pathology , postmortem studies , brain tissue , postmortem changes , neuroscience , biology , medicine
Animal models used to study human aging and neurodegeneration do not display all symptoms of these processes as they are found in humans. Recently, we have shown that many cells in neocortical slices from adult human postmortem brain may survive for extensive periods in vitro. Such cultures may enable us to study age and disease related processes directly in human brain tissue. Here, we present observations on subcortical brain tissue.