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The first Australian experience of heterotopic grafting of cryopreserved ovarian tissue: evidence of establishment of normal ovarian function
Author(s) -
STERN Catharyn J.,
TOLEDO Manuela G.,
HALE Lyndon G.,
GOOK Debra A.,
EDGAR David H.
Publication year - 2011
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.2011.01289.x
Subject(s) - ovarian cortex , cryopreservation , ovarian tissue , ovarian tissue cryopreservation , embryo , follicular phase , biology , grafting , ovary , oocyte , andrology , embryo cryopreservation , fertility preservation , medicine , endocrinology , fertility , microbiology and biotechnology , chemistry , population , environmental health , organic chemistry , polymer
Cryostorage of reproductive potential, in the form of ovarian cortex, for young women about to undergo cytotoxic therapies has been offered clinically for some time. However, the prospects of re‐establishing reproductive function using this tissue remain unclear. We now report reproducible follicular development, oocyte retrieval and embryo development following heterotopic grafting of cryopreserved ovarian cortex which had been stored for over 10 years.