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In Vitro Effect of Tetanus Toxin on GAB A Release from Rat Hippocampal Slices
Author(s) -
Collingridge G. L.,
Thompson P. A.,
Davies J.,
Mellanby J.
Publication year - 1981
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1981.tb04492.x
Subject(s) - tetanus , toxin , hippocampal formation , incubation , in vitro , chemistry , pharmacology , incubation period , dose dependence , biology , neuroscience , biochemistry , endocrinology , immunology , vaccination
Ca 2+ ‐dependent K + ‐stimulated γ‐aminobutyric acid release from rat hippocampal slices was reduced about 30% by pre‐incubation of the slices with 10 4 mouse LD 50 /ml tetanus toxin for 3 h at 37°C.
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