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Treatment of basal cell carcinomas in patients with nevoid basal cell carcinoma syndrome
Author(s) -
Van Der Geer S,
Ostertag JU,
Krekels GAM
Publication year - 2009
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.2008.03040.x
Subject(s) - nevoid basal cell carcinoma syndrome , medicine , imiquimod , cryotherapy , dermatology , basal cell carcinoma , basal cell , modalities , treatment modality , photodynamic therapy , surgery , pathology , social science , chemistry , organic chemistry , sociology
Background Nevoid basal cell carcinoma syndrome (NBCCS) is characterized by the development of multiple basal cell carcinomas (BCCs). A major problem for these patients is the enormous amount of BCCs which can invade in the deep underlying structures, especially in the face. Different treatment modalities are used in these patients; surgical excision, Mohs micrographic surgery, cryotherapy, photodynamic therapy, ablative laser therapy and topical 5% imiquimod. There is no evidence based advice how to treat a NBCCS patient. Objective To give a review of the literature about the possible treatment modalities for the multiple BCCs in NBCCS patients. Results Literature consists mainly of case reports; no evidence based advice how to treat a NBCCS patient exists. Multiple treatments are available (surgical and non‐surgical), and a lot of them can be combined. Treatment in a megasession is an option to diminish the medical and social inconvenience for the patient. Conflicts of interest None declared