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Giant paraovarian myxoma
Author(s) -
Habek Dubravko,
Dmitrovic Branko,
Popovic Zoran,
Karša Matija,
Blažicvic Valerija,
Rupcic Branko,
Vlahovic Mirna Erman,
Marjanovic Ksenija
Publication year - 2006
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.2006.00379.x
Subject(s) - vimentin , medicine , myxoma , pathology , stroma , immunohistochemistry , anatomy , giant cell , leiomyoma , radiology
We present an extremely rare case of a successfully operated giant (6700 g) paraovarian myxoma and uterus myomatosus in a 49‐year‐old woman. Preoperative examination (biochemical investigations, ultrasound and computed tomography scan) and perioperative findings did not identify a malignant tumor so that total abdominal hysterectomy/bilateral salpingo‐oophorectomy and tumorectomy was chosen to treat the patient. Histologically, the tumor was clearly differentiated from the surrounding tissue. In solid regions there were spindle‐shaped cells arranged in sheaves and within the profuse, well‐vascularized myxomatous stroma there were star‐shaped cells. Immunohistochemical analysis showed that tumor cells were positive to vimentin and smooth muscle actin. Electron microscopic analysis showed that tumor cells had ultrastructural characteristics that corresponded to cells in fibroma and thecoma in a profuse intercellular matrix, which confirmed the result of light microscopy.